Effective strategies for reducing food intake are needed to reduce risk of obesity-related cancers. We investigated the effect of low and high glycemic load (GL) diets on satiety and whether satiety varied by body mass index (BMI), gender, and serum leptin. Eighty normal weight (BMI = 18.5-24.9 kg/m2) and overweight/ obese (BMI = 28.0-40.0 kg/m2) adults participated in a randomized, crossover controlled feeding study testing low GL vs. high GL diets. The 28-day diets were isocaloric with identical macronutrient distributions, differing only in GL and fiber. Participants completed visual analog satiety surveys and fasting serum leptin after each 28-day period. T-tests compared mean within- and between-person satiety scores and leptin values. Participants reported 7% greater satiation on the low GL vs. the high GL diet (P = 0.03) and fewer food cravings on the low GL vs. the high GL diet (P 0.001). Compared to males, females reported less hunger (P = 0.05) and more satiety on the low GL vs. the high GL diet (P 0.01). Participants with low body fat (25.0% for men; 32.0% for women) and BMI 25.0 kg/m2 reported study food was tastier on the low GL vs. the high GL diet (P = 0.04 and P = 0.05, respectively). In summary, reducing GL, and/or increasing fiber, may be an effective way to lower calories consumed, improve energy balance, and ultimately reduce cancer risk.View full textDownload full textRelated var addthis_config = { ui_cobrand: "Taylor & Francis Online", services_compact: "citeulike,netvibes,twitter,technorati,delicious,linkedin,facebook,stumbleupon,digg,google,more", pubid: "ra-4dff56cd6bb1830b" }; Add to shortlist Link Permalink http://dx.doi.org/10.1080/01635581.2012.676143
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机译：需要减少食物摄入的有效策略，以减少与肥胖相关的癌症的风险。我们调查了低和高血糖负荷（GL）饮食对饱腹感的影响，以及饱腹感是否因体重指数（BMI），性别和血清瘦素而异。 80名正常体重（BMI = 18.5-24.9 kg / m 2 ）和超重/肥胖（BMI = 28.0-40.0 kg / m 2 ）成人参加了随机交叉试验对照喂养试验，测试低GL与高GL饮食之间的关系。 28天的饮食是等热量的，具有相同的大量营养素分布，仅GL和纤维有所不同。参加者每28天完成一次视觉模拟饱腹感调查，并禁食血清瘦素。 T检验比较了人与人之间的平均饱腹感评分和瘦素值。参与者报告，低GL与高GL饮食相比，饱腹感提高了7％（P = 0.03），而低GL与高GL饮食相比，对食物的渴望减少了（P <0.001）。与男性相比，低GL饮食与高GL饮食相比，女性的饥饿感更少（P = 0.05），饱腹感也更高（P <0.01）。低体脂（男性<25.0％；女性<32.0％）和BMI <25.0 kg / m 2 的参与者报告说，低GL与高GL饮食相比，研究食物更美味（P分别为0.04和P = 0.05）。总之，减少GL和/或增加纤维可能是降低卡路里消耗，改善能量平衡并最终降低癌症风险的有效方法。查看全文下载全文相关的var addthis_config = {ui_cobrand：“ Taylor＆Francis Online”， services_compact：“ citeulike，netvibes，twitter，technorati，可口，linkedin，facebook，stumbleupon，digg，google，更多”，发布：“ ra-4dff56cd6bb1830b”};添加到候选列表链接永久链接http://dx.doi.org/10.1080/01635581.2012.676143
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