MediSPECT: Single photon emission computed tomography system for small field of view small animal imaging based on a CdTe hybrid pixel detector

摘要

We describe MediSPECT, a new scanner developed at University and INFN Napoli, for SPECT studies on small animals with a small field of view (FOV) and high spatial resolution. The CdTe pixel detector (a 256 x 256 matrix of 55 pm square pixels) operating in single photon counting for detection of gamma-rays with low and medium energy (e.g. I-121. 27-35 keV, Tc-99m, 140 keV), is bump bonded to the Medipix2 readout chip. The FOV of the MediSPECT scanner with a coded aperture mask collimator ranges from 6.3 mm (system spatial resolution 110 mu m at 27-35 keV) to 24.3 mm. With a 0.30 mm pinhole the FOV ranges from 2.4 to 29mm (where the system spatial resolution is 1.0 mm at 27-35 keV and 2.0 mm at 140keV). MediSPECT will be used for in vivo imaging of small organs or tissue structures in mouse, e.g., brain, thyroid, heart or tumor. (c) 2006 Elsevier B.V. All rights reserved.