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Evaluation of a high resolution silicon PET insert module

机译:高分辨率硅PET插入模块的评估

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摘要

Conventional PET systems can be augmented with additional detectors placed in close proximity of the region of interest. We developed a high resolution PET insert module to evaluate the added benefit of such a combination. The insert module consists of two back-to-back 1 mm thick silicon sensors, each segmented into 1040 1 mm~2 pads arranged in a 40 by 26 array. A set of 16 VATAGP7.1 ASICs and a custom assembled data acquisition board were used to read out the signal from the insert module. Data were acquired in slice (2D) geometry with a Jaszczak phantom (rod diameters of 1.2-4.8 mm) filled with ~(18)F-FDG and the images were reconstructed with ML-EM method. Both data with full and limited angular coverage from the insert module were considered and three types of coincidence events were combined. The ratio of high-resolution data that substantially improves quality of the reconstructed image for the region near the surface of the insert module was estimated to be about 4%. Results from our previous studies suggest that such ratio could be achieved at a moderate technological expense by using an equivalent of two insert modules (an effective sensor thickness of 4 mm).
机译:常规的PET系统可以通过在感兴趣区域附近放置的其他检测器进行扩充。我们开发了高分辨率的PET插入模块,以评估这种组合的附加优势。插入模块由两个背对背1 mm厚的硅传感器组成,每个传感器分成1040个1 mm〜2个焊盘,以40 x 26的阵列排列。一组16个VATAGP7.1 ASIC和一个定制的组装数据采集板用于从插入模块中读出信号。以充满(〜18)F-FDG的Jaszczak体模(棒直径为1.2-4.8 mm)以切片(2D)几何形状获取数据,并使用ML-EM方法重建图像。考虑了来自插入模块的具有完全和有限角度覆盖的数据,并且组合了三种类型的重合事件。对于插入模块的表面附近的区域,实质上提高了重建图像质量的高分辨率数据的比例约为4%。我们以前的研究结果表明,通过使用等效的两个插入模块(有效传感器厚度为4 mm),可以以中等的技术成本实现该比例。

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