Untersuchung biologischer Adsorbate mittels moderner Quarzmikrogravimetrie

摘要

The quartz crystal microbalance (QCM) is an important technique for biomaterial surface characterization and the examination of cell/surface interactions. The development of modern QCM devices and detailed theoretical models on the viscoelastic damping of transversal shear wave oscillators allowed a detailed investigation of adsorbed protein films and adherent living cells. Applying QCM and complemental techniques we studied the interplay of photochemical polymer surface modifications, protein layers formed by competitive adsorption and anchorage dependent cells like hepatocytes.