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IN BRIEF

机译:在信中

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摘要

There they arel New neurons vital for memory have been seen in a live brain. The work could aid treatments for anxiety and stress disorders. Attila Losonczy at Columbia University Medical Center in New York and his team implanted a tiny microscope into the brains of live mice, the brain cells of which had been modified to make newly made neurons glow. The mice then ran on a treadmill as the team tweaked the surrounding sights, smells and sounds. The researchers paired a small electric shock with some cues, so the mice learned to associate these with an unpleasant experience. They then deactivated the newborn neurons - present in areas of the brain responsible for learning and memory - using optogenetics, which switches off specific cells with light.
机译:在活的大脑中可以看到对记忆至关重要的新神经元。这项工作可以帮助治疗焦虑症和压力症。纽约哥伦比亚大学医学中心的阿提拉·洛森奇(Attila Losonczy)和他的团队将一个微型显微镜植入了活体小鼠的大脑,该小鼠的脑细胞经过了修饰,可以使新产生的神经元发光。然后,当团队调整周围的景点,气味和声音时,老鼠在跑步机上奔跑。研究人员将小型电击与某些线索配对,因此小鼠学会了将它们与不愉快的经历联系起来。然后,他们使用光遗传学使新生神经元失活(存在于负责学习和记忆的大脑区域),该光遗传学用光关闭特定的细胞。

著录项

  • 来源
    《New scientist》 |2016年第3065期|17-18|共2页
  • 作者

  • 作者单位
  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
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  • 入库时间 2022-08-18 02:51:20
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