Comparative neuroimaging in children with cerebral palsy using fMRI and a novel EEG-based brain mapping during a motor task – A preliminary investigation

摘要

Abstract.nPURPOSE: The purpose of this study was to compare topographical maps using a novel EEG-based brain mapping system withnfMRI in normal and children with cerebral palsy (CP) during a grasping motor task.nMETHOD: A normal child (mean±SD=13±0 yrs) and four children with CP (mean±SD = 10.25±2.86 yrs) were recruitednfrom a local community school and medical center. A novel EEG-based brain mapping system with 30 scalp sites (an extensionnof the 10–20 system) and a 3T MR scanner were used to observe cortical activation patterns during a grasping motor task.nDESIGN: Descriptive analysis.nRESULTS: In the EEG brain mapping data, the sensorimotor cortex (SMC) and inferior parietal cortex (IPC) were activated innall of the children. The children with CP showed additional activation areas in the premotor cortex (PMC), superior parietal cortexn(SPC), and prefrontal cortex (PFC). In the fMRI brain mapping data, SMC activation was observed in all of the children, and thenchildren with CP showed additional activation areas in the PMC and primary somatosensory cortex (PSC).nDISCUSSION: The EEG-based topographical maps were equivalent to the maps obtained from fMRI during the grasping motorntask. The results indicate that our novel EEG-based brain mapping system is useful for probing cortical activation patterns innnormal children and children with CP.