Cell death induction by betulinic acid, ceramide and TRAIL in primary glioblastoma multiforme cells

I. Jeremias; H. H. Steiner; A. Benner; K.-M. Debatin; C. Herold-Mende

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Cell death induction by betulinic acid, ceramide and TRAIL in primary glioblastoma multiforme cells

机译：山茱ulin酸，神经酰胺和TRAIL诱导多形性胶质母细胞瘤细胞死亡

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Background. Glioblastoma multiforme (WHO Grade IV, GBM) is the most malignant brain tumour with a mean survival time of less than one year. Betulinic acid, ceramide and TRAIL (TNF-related apoptosis inducing ligand) represent novel therapeutic agents for potential use in GBM.

机译：背景。多形胶质母细胞瘤（WHO IV级，GBM）是最恶性的脑肿瘤，平均生存时间不到一年。桦木酸，神经酰胺和TRAIL（与TNF相关的凋亡诱导配体）代表了可能在GBM中使用的新型治疗剂。

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《Acta Neurochirurgica》 |2004年第7期|721-729|共9页
作者
I. Jeremias; H. H. Steiner; A. Benner; K.-M. Debatin; C. Herold-Mende;
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作者单位

Dr. von Haunersches Kinderspital;

Department of Neurosurgery Section Molecular Biology University Heidelberg;

Central Unit Biostatistics German Cancer Research Center;

University Clinic and Policlinic for Children and Adolescents;

Department of Neurosurgery Section Molecular Biology University HeidelbergDepartment of Head and Neck Surgery University Heidelberg;

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Keywords: Glioblastoma multiforme WHO IV; betulinic acid; ceramide; TRAIL.;

机译：关键词：多形胶质母细胞瘤WHO IV;桦木酸神经酰胺落后。;
入库时间 2022-08-18 01:54:36

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1. PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells. [J] . Yacoub A, Hamed HA, Allegood Cancer research: The official organ of the American Association for Cancer Research, Inc . 2010,第3期

机译：神经酰胺合酶6和硫氧还蛋白的PERK依赖性调节在mda-7 / IL-24诱导的原代人胶质母细胞瘤多形细胞杀伤中起关键作用。
2. Targeted induction of apoptosis in glioblastoma multiforme cells by an MRP3-specific TRAIL fusion protein in vitro. [J] . Liang-Hua Wang, Chang-Wei Ni, Yong-Zhong Lin, Tumour biology : . 2014,第2期

机译：MRP3特异性TRAIL融合蛋白在体外靶向诱导多形性胶质母细胞瘤细胞凋亡。
3. Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo [J] . Kavitha Chandagirikoppal V., Jain Anil K., Agarwal Chapla, Molecular Carcinogenesis . 2015,第11期

机译：亚洲酸在体外和体内诱导胶质母细胞瘤多形细胞内质网应激和凋亡死亡
4. miRNA 128 Induces Cell Death in Glioblastoma Multiforme and Myeloid Leukemia Cell Lines [C] . Banerjee Hirendra, Evans Shayonda, Mahaffey Kelly, Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on . 2012

机译：miRNA 128诱导胶质母细胞瘤和髓样白血病细胞系中的细胞死亡
5. Necrosis induction by various radiation modalities in human glioblastoma multiforme tumor cells versus normal human astrocytes. [D] . Owens, Kathryn Sue. 2012

机译：人胶质母细胞瘤多形肿瘤细胞与正常人星形胶质细胞相比，通过各种辐射方式诱导坏死。
6. Induction of Cell Death by Betulinic Acid through Induction of Apoptosis and Inhibition of Autophagic Flux in Microglia BV-2 Cells [O] . Jeongbin Seo, Juneyoung Jung, Dae Sik Jang, 2017

机译：桦木酸通过诱导小胶质细胞BV-2细胞凋亡和抑制自噬通量来诱导细胞死亡。
7. Novel Therapy for Glioblastoma Multiforme by Restoring LRRC4 in Tumor Cells: LRRC4 Inhibits Tumor-Infitrating Regulatory T Cells by Cytokine and Programmed Cell Death 1-Containing Exosomes [O] . Peiyao Li, Jianbo Feng, Yang Liu, 2017

机译：通过在肿瘤细胞中恢复LRRC4对多形性胶质母细胞瘤的新疗法：LRRC4通过细胞因子和程序性细胞死亡1 - 含有外泌体抑制肿瘤 - 感染调节性T细胞

Cell death induction by betulinic acid, ceramide and TRAIL in primary glioblastoma multiforme cells

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