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Posttranscriptional deregulation of signaling pathways in meningioma subtypes by differential expression of miRNAs

机译:通过miRNA的差异表达来转录后对脑膜瘤亚型信号通路的抑制

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摘要

Micro (mi)RNAs are key regulators of gene expression and offer themselves as biomarkers for cancer development and progression. Meningioma is one of the most frequent primary intracranial tumors. As of yet, there are limited data on the role of miRNAs in meningioma of different histological subtypes and the affected signaling pathways.
机译:微小(mi)RNA是基因表达的关键调节因子,可作为癌症发展和进程的生物标记物。脑膜瘤是最常见的原发性颅内肿瘤之一。迄今为止,关于miRNA在不同组织学亚型和受影响的信号通路中的脑膜瘤的作用的数据还很有限。

著录项

  • 来源
    《Neuro-Oncology》 |2015年第9期|1250-1260|共11页
  • 作者单位

    Univ Saarland, Sch Med, Dept Human Genet, D-66421 Homburg, Germany;

    Univ Saarland, Sch Med, Inst Pathol, D-66421 Homburg, Germany;

    Univ Saarland, Sch Med, Dept Human Genet, D-66421 Homburg, Germany|Univ Saarland, Univ Hosp, Chair Clin Bioinformat, D-66123 Saarbrucken, Germany;

    Univ Saarland, Sch Med, Dept Human Genet, D-66421 Homburg, Germany|Univ Saarland, Univ Hosp, Chair Clin Bioinformat, D-66123 Saarbrucken, Germany;

    Univ Saarland, Sch Med, Dept Human Genet, D-66421 Homburg, Germany;

    Univ Saarland, Sch Med, Dept Human Genet, D-66421 Homburg, Germany|Univ Saarland, Univ Hosp, Chair Clin Bioinformat, D-66123 Saarbrucken, Germany;

    Univ Saarland, Sch Med, Dept Human Genet, D-66421 Homburg, Germany|Univ Saarland, Sch Med, Inst Pathol, D-66421 Homburg, Germany;

    Univ Saarland, Sch Med, Inst Pathol, D-66421 Homburg, Germany;

    Univ Saarland, Univ Hosp, Chair Clin Bioinformat, D-66123 Saarbrucken, Germany;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    histological subtypes; meningioma; miRNA; qRT-PCR;

    机译:组织学亚型;脑膜瘤;miRNA;qRT-PCR;

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