Short-term increase of glucose concentration in PDS results in extensive removal and high glycation level of vital proteinsn during continuous ambulatory peritoneal dialysis

摘要

Background. The effect of clearance of so-called middle- and high-molecular weight proteins on clinical outcome of patients treated by peritoneal dialysis is still a matter of debate. In our present study, we investigated the impact of short-time alteration of the glucose concentration and the osmolarity of the peritoneal dialysis solution (PDS) on protein removal.