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Kidney disease in cardiology

机译:肾脏病的心脏病学

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摘要

Topics covered in this review include the relation of estimated glomerular filtration rate, proteinuria and outcome; sudden cardiac death; contrast-induced acute kidney injury (CI-AKI); imaging; clinical trials targeting cardiovascular disease in chronic kidney disease (CKD) patients; and treatment of ischemic heart disease and valvular disease. Several studies reinforce the importance of CKD in predicting mortality and make a case for redefining CKD to incorporate levels of proteinuria in the staging system. Another study provides support for using a combination of echocardiography and cardiac biomarkers for cardiac risk stratification in dialysis patients. Two studies reveal ongoing interest in and difficulty preventing CI-AKI. One study discusses chest ultrasound to detect pulmonary congestion and potentially guide ultrafiltration and volume removal in dialysis patients. Several clinical trials assess folic acid, statins and aspirin for prevention of future cardiovascular events in CKD patients. Finally, several studies compare the use of drug-eluting and bare metal stents in dialysis patients, discuss methods of surgical coronary artery revascularization in dialysis patients and describe testing allopurinol as a treatment for ischemic heart disease in non-renal patients.
机译:这篇综述涉及的话题包括估计的肾小球滤过率,蛋白尿与预后的关系。心源性猝死;造影剂诱发的急性肾损伤(CI-AKI);成像针对慢性肾脏病(CKD)患者的心血管疾病的临床试验;和治疗缺血性心脏病和瓣膜疾病。多项研究强调了CKD在预测死亡率中的重要性,并为重新定义CKD在分期系统中纳入蛋白尿水平提供了依据。另一项研究为将超声心动图和心脏生物标志物联合用于透析患者的心脏风险分层提供了支持。两项研究表明,人们对CI-AKI持续存在兴趣并难以预防。一项研究讨论了胸部超声检查以检测肺部充血并可能指导透析患者的超滤和去除体积。多项临床试验评估叶酸,他汀类药物和阿司匹林在CKD患者中预防未来心血管事件的发生。最后,一些研究比较了在透析患者中​​使用药物洗脱支架和裸金属支架的情况,讨论了在透析患者中​​进行手术冠状动脉血运重建的方法,并描述了测试别嘌呤醇作为非肾脏患者缺血性心脏病的治疗方法。

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