Worlds in common through NF-κB

摘要

A transcription factor that regulates cell activity in the immune system and a human syndrome that affects face and limb development seem worlds apart. On pages 611 and 615 of this issue, however, Kanegae et al.1 and Bushdid et al.2 report an unsuspected role of NF-κB that brings these worlds together in the context of chick limb development.