DNA-binding proteins meet their mismatch

Kundert Kale; Fraser James S.

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DNA-binding proteins meet their mismatch

机译：DNA结合蛋白符合其不匹配

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摘要

Mismatches are alterations in DNA that prevent the bases on each strand of the double helix from aligning correctly. It emerges that mismatches can bend DNA into favourable conformations for binding by proteins.

机译：不匹配是DNA中的改变，防止双螺旋的每条股线上的碱正确对准。它出现了不匹配可以将DNA弯曲成有利的蛋白质结合的构象。

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来源
《Nature》 |2020年第7833期|199-200|共2页
作者
Kundert Kale; Fraser James S.;
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作者单位

Harvard Univ Wyss Inst Biol Inspired Engn Boston MA 02138 USA;

Univ Calif San Francisco Dept Bioengn & Therapeut Sci San Francisco CA 94158 USA;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类
关键词
Molecular biology;

机译：分子生物学;

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专利

1. Analysis and classification of DNA-binding sites in single-stranded and double-stranded DNA-binding proteins using protein information [J] . Wei Wang, Juan Liu, Yi Xiong, IET systems biology . 2014,第4期

机译：使用蛋白质信息分析和分析单链和双链DNA结合蛋白中的DNA结合位点
2. Highly repeated sites in the apolipoprotein(a) gene recognized by methylated DNA-binding protein, a sequence-specific DNA-binding protein. [J] . K C Ehrlich, M Ehrlich Molecular and Cellular Biology . 1990,第9期

机译：载脂蛋白（a）基因中高度重复的位点，被甲基化DNA结合蛋白（一种序列特异性DNA结合蛋白）识别。
3. Nucleotides Sequestered at Different Subsite Loci Within DNA-Binding Pockets of Two OB-Fold Single-Stranded DNA-Binding Proteins Are Unstacked to Different Extents [J] . Hieu N. Nguyen, Liang Zhao, Carla W. Gray, Biopolymers: Original Research on Biomolecules and Biomolecular Assemblies . 2013,第7期

机译：隔离在两个OB折叠单链DNA结合蛋白的DNA结合口袋内的不同亚位点位点的核苷酸被堆叠到不同程度。
4. Limited Proteolysis and Oxidative Surface Mapping for Characterization of the DNA-Binding Domain of Mismatch Repair Protein Pms1 by Mass Spectrometry [C] . Allison N. Schorzman, Jenny M. Cutalo, Lars C. Pedersen, ASMS Conference on Mass Spectrometry and Allied Topics . 2008

机译：有限的蛋白水解和氧化表面映射，用于表征错配修复蛋白PMS1的DNA结合结构域通过质谱法
5. Characterization of the sigma factor proteins and the DNA-binding protein EUO of Chlamydia. [D] . Blackwell, Cory L. 2011

机译：衣原体的sigma因子蛋白和DNA结合蛋白EUO的表征。
6. Highly repeated sites in the apolipoprotein(a) gene recognized by methylated DNA-binding protein, a sequence-specific DNA-binding protein. [O] . K C Ehrlich, M Ehrlich 1982

机译：载脂蛋白（a）基因中高度重复的位点，被甲基化DNA结合蛋白（一种序列特异性DNA结合蛋白）识别。
7. DNA-binding proteins meet their mismatch [O] . Kale Kundert, James S. Fraser 2020

机译：DNA结合蛋白符合其不匹配

DNA-binding proteins meet their mismatch

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