Melanoma troops massed

摘要

In most Western countries, the incidence of melanoma - a form of skin cancer linked to exposure to sunlight - doubles roughly every decade. Early removal of melanoma lesions leads to a good prognosis, but the outlook for patients with advanced melanoma is often bleak owing to a lack of effective treatments. To develop better therapies, a deeper understanding of this cancer's biology is needed. To this end, a paper published by Old and colleagues' in Molecular Cell, which reports on a new use of a proteomics technique to identify molecules regulating melanoma-cell behaviour, is a welcome advance.