Still much to learn about mice

摘要

The mouse is the undisputed king of laboratory science. It achieved its royal status after it was chosen as the first mammal-after the human - to have its genome sequenced. Understanding the genome made it possible to develop new molecular technologies to make mutant mice, and scientists have made them by the thousand. They have also used these mutant mice to illuminate how genes and the molecular pathways they control operate in health and disease. This has also cast some welcome, if indirect,light on human diseases.