Evaluation of Basis Function and Linear Least Squares Methods for Generating Parametric Blood Flow Images Using 15O-Water and Positron Emission Tomography

Ronald Boellaard PhD; Paul Knaapen MD; Abraham Rijbroek MD; Gert J. J. Luurtsema; Adriaan A. Lammertsma PhD

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Evaluation of Basis Function and Linear Least Squares Methods for Generating Parametric Blood Flow Images Using 15O-Water and Positron Emission Tomography

机译：基于15 O-水和正电子发射断层扫描技术生成参数血流图像的基函数和线性最小二乘法方法的评估

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摘要

Parametric analysis of 15O-water positron emission tomography (PET) studies allows determination of blood flow (BF), perfusable tissue fraction (PTF), and volume of distribution (V d) with high spatial resolution. In this paper the performance of basis function and linear least squares methods for generating parametric flow data were evaluated.

机译：通过对15 O-水正电子发射断层扫描（PET）研究的参数分析，可以以高空间分辨率确定血流量（BF），可灌注组织分数（PTF）和分布体积（V d ）。本文评估了基函数和线性最小二乘法生成参数流数据的性能。

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《Molecular Imaging and Biology》 |2005年第4期|273-285|共13页
作者
Ronald Boellaard PhD; Paul Knaapen MD; Abraham Rijbroek MD; Gert J. J. Luurtsema; Adriaan A. Lammertsma PhD;
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作者单位

Department of Nuclear Medicine and PET Research VU University Medical Center 1007 MB Amsterdam The Netherlands;

Department of Cardiology VU University Medical Center Amsterdam The Netherlands;

Department of Surgery VU University Medical Center Amsterdam The Netherlands;

Department of Nuclear Medicine and PET Research VU University Medical Center 1007 MB Amsterdam The Netherlands;

Department of Nuclear Medicine and PET Research VU University Medical Center 1007 MB Amsterdam The Netherlands;

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正文语种 eng
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关键词
Positron emission tomography; Parametric images; Blood flow; 15O-water; Linear least squares; Basis function; Accuracy; Precision;

机译：正电子发射断层扫描;参数图像;血流;15O-水;线性最小二乘;基函数;精度;精度;

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1. Evaluation of basis function and linear least squares methods for generating parametric blood flow images using 15O-water and Positron Emission Tomography. [J] . Boellaard R, Knaapen P, Rijbroek A, Molecular imaging and biology: MIB : the official publication of the Academy of Molecular Imaging . 2005,第4期

机译：评估使用15O-水和正电子发射断层摄影术生成参数化血流图像的基函数和线性最小二乘法。
2. Parametric Imaging of Myocardial Blood Flow with 15O-Water and PET Using the Basis Function Method. [J] . Watabe H, Jino H, Kawachi N, The Journal of Nuclear Medicine . 2005,第7期

机译：使用基础函数方法用15O-水和PET对心肌血流进行参数化成像。
3. Parametric Imaging of Myocardial Blood Flow with 15O-Water and PET Using the Basis Function Method [J] . Hiroshi Watabe, Hiroshi Jino, Naoki Kawachi, The Journal of Nuclear Medicine . 2005,第7期

机译：基于基函数法的15O-水和PET对心肌血流的参数成像
4. Development of Fully Automatic Technique to Generate Parametric Images of Myocardial Blood Flow with 15{sup left}O-Water and Positron Emission Tomography using Basis Function Method [C] . Hiroshi Watabe, Kazuhiro Koshino, Noboru Teramoto, IEEE Nuclear Science Symposium . 2005

机译：使用基函数方法产生15 {Sup左} O-Water和正电子发射断层扫描产生心肌血流参数图像的全自动技术
5. Cerebral Blood Flow Measurements Using Carotid Artery Image-Derived Input Functions in Positron Emission Tomography. [D] . Fung, Edward Komin. 2013

机译：在正电子发射断层扫描中使用颈动脉图像衍生的输入函数进行脑血流量测量。
6. Positron emission tomography/magnetic resonance hybrid scanner imaging of cerebral blood flow using 15O-water positron emission tomography and arterial spin labeling magnetic resonance imaging in newborn piglets [O] . Julie B Andersen, William S Henning, Ulrich Lindberg, 2015

机译：15O-水正电子发射断层扫描和动脉自旋标记磁共振成像对新生仔猪脑血流的正电子发射断层扫描/磁共振混合扫描仪成像
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机译：在使用新的扩张型心肌病的患者缓和EPOSTERS1385Longitudinal应变评估加速DENSE sequence1407Simultaneous T1和T2与CABIRIA心脏定量：在4维流动的加速算法初始临床experience1423Head对头比较CMR1502Left心室功能和尺寸由混合心脏正电子发射断层摄影术评价 - 磁性共振：由两个modalities1510Left庭派生左室射血分数和心室体积的个体间的比较，在1.5和3特斯拉评估心血管磁共振 - 免费的年龄和性别effects1514Comparison呼吸心脏MRI径向技术标准的多屏气电影SSFP CMR技术的LV卷和Function1536Self-导航自由呼吸各向同性3D整个心脏相位敏感反转恢复磁共振导航仪没有检测右Ventricu心肌infarction1547Assessment的评估拉尔菌株使用心肌变形恢复半自动技术：初步经验和正常Values1586Tissue跟踪心肌变形分析和预测左室重构急性心肌infarction1589Investigating策略优化31P MRS临床心脏在3T：初始Results1620Quantitative标准的先天缺失的诊断心包心脏磁Resonance1632Widespread组织损伤急性心肌梗死时：证据先进CMR relaxometry1322Computed CT冠状动脉成像与压力心脏磁共振对症的管理吻合血管患者：成本效益研究（战略研究）1339Comparison低与高剂量钆布醇在1.5特斯拉晚钆增强成像的临床可行性，在中间型地贫心脏并发症的预测study1347Multi参数心脏核磁共振的前瞻性德穆尔心血管磁共振的ticenter Study1461Prognostic价值衍生心肌纤维化指标在住院的急性期CMR的心脏移植recipients1523The作用：改变基于CMR-paradigms1542Preoperative比分预测缺血性心脏衰竭patients1555Excellent响应速度外科左心室重建心脏再同步化后心室反应治疗与磁共振imaging1626The ECG导引作为心脏磁共振成像致心律失常性基板的在ST段抬高心肌infarction1340Pathological在风险评估经历在3.0T CMR T1映射的室性早搏contractions1649Comparison和血管造影APPROACH分数区域消融患者的预测左束支传导疾病的患者与非缺血性心肌病相关因素：心血管磁共振study1342Myocardial重塑和纤维化nonischaemic扩张型心肌病：在从在由心血管磁性resonance1622Persistent心肌炎症评估肥厚型心肌病的纤维化和收缩功能障碍之间心血管磁性resonance1411The协会由于心肌内出血景点在再灌注STEMI为先导，以不利的LV重塑 - 从低的多参数mapping1566Semiquantitative分析和高的b值DWI的见解为在心脏MRI检测冠状动脉疾病急性myocarditis1567Value在结节性硬化症complex1578Papillary肌肉初诊收缩期Dysfunction1570Usefulness心脏磁共振检测心肌水肿提供进一步的深入了解肥大心脏：心血管磁共振study1627Diagnostic和CMR定时的临床意义（早期与晚）患者肌钙蛋白阳性的急性冠脉综合征和通畅的冠状动脉：表1。

Evaluation of Basis Function and Linear Least Squares Methods for Generating Parametric Blood Flow Images Using 15O-Water and Positron Emission Tomography

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