Monitoring Response to Radiotherapy in Human Squamous Cell Cancer Bearing Nude Mice: Comparison of 2′-deoxy-2′-[18F]fluoro-d-glucose (FDG) and 3′-[18F]fluoro-3′-deoxythymidine (FLT)

Carla F. M. Molthoff; Bianca M. Klabbers; Johannes Berkhof; Jasper T. Felten; Marcelle van Gelder; Albert D. Windhorst; Ben J. Slotman; Adriaan A. Lammertsma

首页> 外文期刊>Molecular Imaging and Biology >Monitoring Response to Radiotherapy in Human Squamous Cell Cancer Bearing Nude Mice: Comparison of 2′-deoxy-2′-[18F]fluoro-d-glucose (FDG) and 3′-[18F]fluoro-3′-deoxythymidine (FLT)

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Monitoring Response to Radiotherapy in Human Squamous Cell Cancer Bearing Nude Mice: Comparison of 2′-deoxy-2′-[18F]fluoro-d-glucose (FDG) and 3′-[18F]fluoro-3′-deoxythymidine (FLT)

机译：监测裸鼠人鳞状细胞癌对放射治疗的反应：2'-deoxy-2'-[18 F]氟-d-葡萄糖（FDG）和3'-[18 F ]氟-3'-脱氧胸苷（FLT）

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摘要

The uptake of 3′-[18F]fluoro-3′-deoxythymidine (FLT), a proliferation marker, was measured before and during fractionated radiotherapy to evaluate the potential of FLT-positron emission tomography (PET) imaging as an indicator of tumor response compared to 2′-deoxy-2′-[18F]fluoro-d-glucose (FDG).

机译：在分级放疗之前和期间测量了3'-[18F]氟-3'-脱氧胸腺嘧啶核苷（FLT）的摄取，以评估FLT-正电子发射断层扫描（PET）成像的潜力与2'-deoxy-2'-[18 F]氟-d-葡萄糖（FDG）相比，肿瘤反应的指标。

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来源
《Molecular Imaging and Biology》 |2007年第6期|340-347|共8页
作者
Carla F. M. Molthoff; Bianca M. Klabbers; Johannes Berkhof; Jasper T. Felten; Marcelle van Gelder; Albert D. Windhorst; Ben J. Slotman; Adriaan A. Lammertsma;
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作者单位

Department of Nuclear Medicine and PET Research VU University Medical Center P.O. Box 7057 1007 Amsterdam The Netherlands;

Department of Radiotherapy VU University Medical Center Amsterdam The Netherlands;

Department of Epidemiology and Biostatistics VU University Medical Center Amsterdam The Netherlands;

Department of Nuclear Medicine and PET Research VU University Medical Center P.O. Box 7057 1007 Amsterdam The Netherlands;

Department of Nuclear Medicine and PET Research VU University Medical Center P.O. Box 7057 1007 Amsterdam The Netherlands;

Department of Nuclear Medicine and PET Research VU University Medical Center P.O. Box 7057 1007 Amsterdam The Netherlands;

Department of Radiotherapy VU University Medical Center Amsterdam The Netherlands;

Department of Nuclear Medicine and PET Research VU University Medical Center P.O. Box 7057 1007 Amsterdam The Netherlands;

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原文格式 PDF
正文语种 eng
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关键词
FDG; FLT; PET; Radiotherapy; Response monitoring; Head and neck xenograft model;

机译：FDG;FLT;PET;放射治疗;反应监测;头颈部异种移植模型;

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1. Monitoring response to radiotherapy in human squamous cell cancer bearing nude mice: comparison of 2'-deoxy-2'-(18F)fluoro-D-glucose (FDG) and 3'-(18F)fluoro-3'-deoxythymidine (FLT). [J] . Molthoff CF, Klabbers BM, Berkhof J, Molecular imaging and biology: MIB : the official publication of the Academy of Molecular Imaging . 2007,第6期

机译：监测携带人鳞状细胞癌的裸鼠对放射疗法的反应：2'-脱氧-2'-（18F）氟-D-葡萄糖（FDG）和3'-（18F）氟-3'-脱氧胸苷（FLT）的比较。
2. Early monitoring of response to antimetabolic treatment of gemcitabine: A comparison of 18F-FLT and 18F-FDG uptake in Patu 8988 human pancreatic carcinoma cells [J] . DENG Shengming, ZHANG Bin, WU Yiwei, 核技术（英文版） . 2011,第005期

机译：吉西他滨抗代谢治疗的早期监测反应：Patu 8988人胰腺癌细胞摄取18F-FLT和18F-FDG的比较
3. Early response monitoring with 18F-FDG PET and cetuximab-F(ab′)2-SPECT after radiotherapy of human head and neck squamous cell carcinomas in a mouse model [J] . VanDijkL.K., BoermanO.C., FranssenG.M., The Journal of Nuclear Medicine . 2014,第10期

机译：小鼠模型中人头颈部鳞状细胞癌放疗后用18F-FDG PET和西妥昔单抗-F（ab'）2-SPECT进行早期反应监测
4. Non-invasive and real-time monitoring of molecular targeting therapy for lymph node and peritoneal metastasis in nude mice bearing xenografts of human colorectal cancer cells tagged with GFP and DsRed [C] . Hayao Nakanishi, Masayasu Hara, Yuzuru Ikehara, Genetically Engineered and Optical Probes for Biomedical Applications IV; Progress in Biomedical Optics and Imaging; vol.8 no.26; Proceedings of SPIE-The International Society for Optical Engineering; vol.6449 . 2007

机译：非侵入性实时监测分子靶向疗法对带有GFP和DsRed标签的人大肠癌细胞异种移植的裸鼠淋巴结和腹膜转移的作用
5. 18f-FDG PET/CT to measure glucose metabolism of various breast cancer cell lines in vivo. [D] . Agrawal, Madhav. 2013

机译：18f-FDG PET / CT用于测量体内各种乳腺癌细胞系的葡萄糖代谢。
6. Monitoring Response to Radiotherapy in Human Squamous Cell Cancer Bearing Nude Mice: Comparison of 2′-deoxy-2′-18Ffluoro-d-glucose (FDG) and 3′-18Ffluoro-3′-deoxythymidine (FLT) [O] . Carla F. M. Molthoff, Bianca M. Klabbers, Johannes Berkhof, -1

机译：监测裸鼠人鳞状细胞癌对放射治疗的反应：2-脱氧-2-18F氟-d-葡萄糖（FDG）与3-18F氟-3-脱氧胸苷（FLT）的比较
7. Monitoring Response to Radiotherapy in Human Squamous Cell Cancer Bearing Nude Mice: Comparison of 2′-deoxy-2′-[18F]fluoro-d-glucose (FDG) and 3′-[18F]fluoro-3′-deoxythymidine (FLT) [O] . Molthoff, Carla F. M., Klabbers, Bianca M., Berkhof, Johannes, 2007

机译：监测裸鼠人鳞状细胞癌对放射治疗的反应：2'-脱氧-2'-[18F]氟-d-葡萄糖（FDG）与3'-[18F]氟-3'-脱氧胸苷（FLT）的比较

Monitoring Response to Radiotherapy in Human Squamous Cell Cancer Bearing Nude Mice: Comparison of 2′-deoxy-2′-[18F]fluoro-d-glucose (FDG) and 3′-[18F]fluoro-3′-deoxythymidine (FLT)

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