Monitoring Proteins Using In Vivo Near-Infrared Time-Domain Optical Imaging after 2-O-Hexyldiglycerol-Mediated Transfer to the Brain

Petra Hülper; Christian Dullin; Wilfried Kugler; Max Lakomek; Bernhard Erdlenbruch

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Monitoring Proteins Using In Vivo Near-Infrared Time-Domain Optical Imaging after 2-O-Hexyldiglycerol-Mediated Transfer to the Brain

机译：2-O-己二甘油介导转移到大脑后，使用体内近红外时域光学成像监测蛋白质。

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摘要

The aim of the present study was to gain insight into the penetration, biodistribution, and fate of globulins in the brain after 2-O-hexyldiglycerol-induced blood–brain barrier opening.

机译：本研究的目的是深入了解2-O-己基二甘油诱导的血脑屏障开放后，球蛋白在脑内的渗透，生物分布和命运。

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来源
《Molecular Imaging and Biology》 |2011年第2期|p.275-283|共9页
作者
Petra Hülper; Christian Dullin; Wilfried Kugler; Max Lakomek; Bernhard Erdlenbruch;
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作者单位

Kinderklinik der Universität Göttingen, Robert-Koch-Str. 40, 37099, Göttingen, Germany;

Radiologische Abteilung Universität Göttingen, Robert-Koch-Str. 40, 37099, Göttingen, Germany;

Kinderklinik der Universität Göttingen, Robert-Koch-Str. 40, 37099, Göttingen, Germany;

Kinderklinik der Universität Göttingen, Robert-Koch-Str. 40, 37099, Göttingen, Germany;

Kinderklinik der Universität Göttingen, Robert-Koch-Str. 40, 37099, Göttingen, Germany;

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正文语种 eng
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关键词
BBB opening; 2-O-Hexyldiglycerol; Anti TGF-β antibody 1D11; Alexa Fluor 680; Cy5.5; Time-domain optical imaging;

机译：BBB开放;2-O-己基二甘油;抗TGF-β抗体1D11;Alexa Fluor 680;Cy5.5;时域光学成像;

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专利

1. Monitoring proteins using in vivo near-infrared time-domain optical imaging after 2-O-hexyldiglycerol-mediated transfer to the brain. [J] . Hulper P, Dullin C, Kugler W, Molecular imaging and biology: MIB : the official publication of the Academy of Molecular Imaging . 2011,第2期

机译：2-O-己基二甘油介导转移到大脑后，使用体内近红外时域光学成像监测蛋白质。
2. Nitroreductase, a near-infrared reporter platform for in vivo time-domain optical imaging of metastatic cancer [J] . McCormackE., SildenE., WestR.M., Cancer research: The official organ of the American Association for Cancer Research, Inc . 2013,第4期

机译：硝基还原酶，一种用于转移癌的体内时域光学成像的近红外报告平台
3. In Vivo Biodistribution And Lifetime Analysis Of Cy5.5-conjugated Rituximab In Mice Bearing Lymphoid Tumor Xenograft Using Time-domain Near-infrared Optical Imaging [J] . Stefania Biffi, Chiara Garrovo, Paolo Macor, Molecular imaging . 2008,第6期

机译：Cy5.5结合的利妥昔单抗在小鼠淋巴肿瘤异种移植物中的体内生物分布和寿命分析时域近红外光学成像。
4. In-vivo resolution of two near-infrared fluorophores by time-domain diffuse optical imaging [C] . Walter Akers, Samuel Achilefu Genetically Engineered and Optical Probes for Biomedical Applications IV; Progress in Biomedical Optics and Imaging; vol.8 no.26; Proceedings of SPIE-The International Society for Optical Engineering; vol.6449 . 2007

机译：时域漫射光学成像在体内分辨两个近红外荧光团
5. A Wearable Near-Infrared Diffuse Optical System for Monitoring in Vivo Breast Tumor Hemodynamics during Chemotherapy Infusions [D] . Teng, Fei. 2018

机译：一种可穿戴近红外漫射光学系统，用于在化疗输注期间在体内乳腺肿瘤血液动力学中监测
6. Monitoring Proteins Using In Vivo Near-Infrared Time-Domain Optical Imaging after 2-O-Hexyldiglycerol-Mediated Transfer to the Brain [O] . Petra Hülper, Christian Dullin, Wilfried Kugler, -1

机译：2-O-己二甘油介导转移到大脑后使用体内近红外时域光学成像监测蛋白质。
7. Monitoring Proteins Using In Vivo Near-Infrared Time-Domain Optical Imaging after 2-O-Hexyldiglycerol-Mediated Transfer to the Brain [O] . Petra Hülper, Christian Dullin, Wilfried Kugler, 2010

机译：2-O-己二甘油介导转移到大脑后，使用体内近红外时域光学成像监测蛋白质。

Monitoring Proteins Using In Vivo Near-Infrared Time-Domain Optical Imaging after 2-O-Hexyldiglycerol-Mediated Transfer to the Brain

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