Application of Isotope Dilution to the Determination of Anthracene in Environmental Samples by Headspace Solid-Phase Microextraction and Gas Chromatography–Mass Spectrometry

摘要

A method using headspace solid-phase microextraction (HS-SPME) followed by gas chromatography–mass spectrometry with selected ion monitoring (GC–MS, SIM) has been developed for the determination of trace amounts of anthracene in sea water, wastewater, honey and saliva samples. Anthracene was extracted on to a fused-silica fibre coated with 85 µm polyacrylate (PA). Quantification of anthracene was carried out by isotope dilution mass spectrometry. The detection limit and the quantification limit found were 0.02 and 0.06 ng mL−1, respectively. The method was validated by analysis of spiked matrix samples and used to investigate the presence of anthracene above the stated detection limit in sea water, wastewater, honey and saliva samples.