Significant heterogeneity between centers during early evaluation of the first Turkish multi-centric study in the treatment of childhood acute lymphoblastic leukemia

摘要

The key of success in the treatment of pediatric acute lymphoblastic leukemia (ALL) has been the conduct of multi-centric clinical studies. With the aim of repeating the favorable results reported by the BFM group and reaching uniformity in diagnosis and treatment, the first Turkish multi-centric study in the treatment of pediatric ALL, BFM-TR ALL 2000, was opened to patient accrual in January 2000.