Lipid lowering and antioxidant activity of flavones in triton treated hyperlipidemic rats

摘要

Flavones are plant derived polyphenolic compounds which are consumed by our diet. Epidemiological studies indicating that high dietary intake of flavones reduces the risk of mortality due to coronary heart disease. The lipid lowering action of flavones—myricetin, rutin, naringenin-7-rhamnoglucosides and naringenin hydrates has been studied in triton treated hyperlipidemic rats (in vivo) and antioxidant activity (in vitro). Among these myricetin and naringenin hydrate showed potent antidyslipidemic and antioxidant activities. The antidyslipidemic and antioxidant activities of these flavones may help in prevention of hyperlipidemia and related cardiovascular diseases.