Physicochemical and biological assessment of PEEK composites embedding natural amorphous silica fibers for biomedical applications

摘要

The main aim of this study was to assess the physicochemical and biological properties of a novel poly(ether ether ketone) (PEEK) composite containing 30%wt natural amorphous silica fibers (NASF). PEEK and NASF powders were previously functionalized by atomization and citric acid in order to enhance adhesion between polymeric matrix and fillers. Then, composites were produced by cold compression molding technique at 350 ℃ for 3 h. Materials were characterized by chemical, microstructural, thermophysical, mechanical and cytotoxic analysis. The results of the mechanical assays showed that the incorporation fibers increased the elastic modulus of the resultant PEEK composite in 56% while its microhardness increased in 26.7%. Chemical and microscopic analyses detected a good interfacial adhesion between PEEK and NASF. The results of the cytotoxicity assays indicated that PEEK/NASF composites stimulated the metabolic activity of fibroblasts and therefore a high cytocompatibility was noticed. PEEK composites embedding natural amorphous silica fibers revealed a high potential to be used in medicine and dentistry replacing several polymeric and composite materials.