Fabrication of ordered konjac glucomannan microfiber arrays via facile microfluidic spinning method

摘要

The exploration of methods to produce biocompatible materials in ultrasmall scales is of great scientific and technological interest. We reported a microfluidic spinning technology (MST) for fabrication of microfibers with a novel biocompatible material, konjac glucomannan (KGM) as the main material combined with sodium polyacrylate (PAAS). These as-produced KGM/PAAS microfibers are consistent and uniform in size with an average width of 100 mu m. Also, these microfibers can easily arrange to microarrays and microgrids, facilely forming a useful platform for molecules recognition of amines. Moreover, the nontoxicity of KGM developed an ofloxacin loaded KGM microfibers present potential application in wound dressing. This strategy contributes a facile pathway on the construction of biomaterial microfibers by using polysaccharides as the precursors. (C) 2017 Published by Elsevier B.V.