Influence of biological lubricant on the morphology of UHMWPE wear particles generated with microfabricated surface textures

摘要

Immunological response induced by wear particles of ultra-high molecular weight polyethylene (UHMWPE) has been recognized as the major factor causing the failure of total joint replacements. A previous study has applied surface texturing techniques to generate UHMWPE wear particles with specific size and shape to study the effects of particle size and shape on osteolysis.