Xenobiotic Biotransformation Enzyme Gene Expression in Early Larval Stages of Plaice

摘要

cDNA probes were utilized to determine the pattern of expression of genes coding for pollutant biotransformation enzymes and systems for detoxication of preox- idation products in eggs and the early stages of plaice laveal developmet. The presence of mRNAs for metallothionein and glutathione S-transferase in eggs indicates that the potential for oxidative defence may be present in fertilized eggs. Genes for the enzymes non-specific carboxylesterase and phenol UDP-glucur- onosyl transferase, which have roles in the metabolism of endobiotic substances as well as pollutants, showed a peak in expression at hatch.