Effects of buprenorphine on body temperature, locomotor activity and cardiovascular function when assessed by telemetric monitoring in rats

摘要

We read with great interest, the recent article in Laboratory Animals by IIbäck et al. (2008). This research adds to the growing research data on buprenorphine as an analgesic in laboratory rodents. The authors' thoughtful discussion helped put their findings in perspective. As we read the article, however, we felt a couple of points deserved further clarification: