Allylsilanes as Carbon Nucleophiles in Intramolecular Pd(Ⅱ)-Catalyzed 1,4-Addition to Conjugated Dienes

摘要

We have shown that allylsilanes can be used as carbon nucleophiles acting as "masked carbanions" in Pd(Ⅱ)-catalyzed carboannulations to 1,3-dienes, in a process that leads to stereodefined 1,4-functionalization of the diene. To the best of our knowledge this is the first example of nucleophilic attack by an allylsilane on an olefin coordinated to a metal.