Olefin Metathesis in Cyclic Ether Formation. Direct Conversion of Olefinic Esters to Cyclic Enol Ethers with Tebbe-Type Reagents

摘要

The olefin metathesis reaction is rapidly emerging as a powerful tool in organic synthesis. Of particular interest are ring forming metathesis reactions catalyzed by transition metal complexes, several elegant examples of which have recently appeared.-Despite the successes of this general approach to ring construction, much remains to be improved in terms of scope, convenience, and generality. In this communication we report a new strategy, based on the olefin metathesis reaction, for the generation of cyclic enol ethers directly from olefin esters using the Tebbe or the Petasis reagents.