Enantioselective Crystal Growth of Leucine on a Self-Assembled Monolayer with Covalently Attached Leucine Molecules

摘要

Monolayer films with an ordered molecular arrangement, such as Langmuir monolayers at the air/solution interface, provide sites for crystal nucleation and affect the growth of crystals beneath the monolayer. Self-assembled monolayers (SAMs) are also reported to influence the nucleation and growth of molecular crystals formed on the SAMs. The monolayer-induced crystallization is important from the viewpoint of molecular recognition at the interface between the monolayer and solution. On the other hand, the attachment of amine molecules on the SAM with amide linkage formation enables one to immobilize either one of the two enantiomeric forms of chiral amino acids, and the enantiomer-attached SAM thus prepared is expected to play a significant role in elucidating crystallization phenomena on the SAM.