A Multifunctional Pasteurella multocida Sialyltransferase:A Powerful Tool for the Synthesis of Sialoside Libraries

摘要

Sialic acid (Sia)-containing structures play important roles in cellular recognition and communication.Chemical sialylation is considered as one of the most difficult glycosylation reactions due to the hindered tertiary anomeric center and the lack of a neighboring participating group in sialic acids.