Blue Ferrocenium Azurin: An Organometalloprotein with Tunable Redox Properties

摘要

Organometallic compounds are known to be very efficient in redox and catalytic reactions.It is thus surprising that only a limited number of organometallic compounds are found in proteins.While more organometalloproteins may be discovered in nature,specific incorporation of organometallic compounds into proteins may allow us to learn guiding principles for designing organometalloproteins and to prepare novel proteins with functional properties that combine benefits of both organometallic compounds (such as new and efficient catalytic activities) and proteins (such as water solubility and high regio- and enantioselectivity).It will make an important contribution to the emerging area of bioorganometallic chemistry.