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Explicit Treatment of Spin Labels in Modeling of Distance Constraints from Dipolar EPR and DEER

机译:偶极子EPR和DEER距离约束建模中的自旋标签的显式处理

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摘要

We describe here a method for enhancing the utility of dipolar- EPR distances as constraints in modeling protein structures by explicit incorporation of the spin labels.We show that accounting for the probe conformation and tether length increases accuracy of distance measures 2-fold.
机译:我们在这里描述了一种通过显式引入自旋标记来增强偶极子EPR距离作为约束蛋白结构模型的工具的方法。我们表明,考虑探针构象和系链长度可使距离测量的准确性提高2倍。

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  • 来源
    《Journal of the American Chemical Society》 |2005年第26期|p.9334-9335|共2页
  • 作者单位

    Biosystems Research Department,Sandia National Laboratories,Livermore,California,Institute of Molecular Biophysics,The National High Magnetic Field Laboratory,Department of Biological Sciences,Florida State University,Tallahassee,Florida,and Departme;

    Biosystems Research Department,Sandia National Laboratories,Livermore,California,Institute of Molecular Biophysics,The National High Magnetic Field Laboratory,Department of Biological Sciences,Florida State University,Tallahassee,Florida,and Departme;

    Biosystems Research Department,Sandia National Laboratories,Livermore,California,Institute of Molecular Biophysics,The National High Magnetic Field Laboratory,Department of Biological Sciences,Florida State University,Tallahassee,Florida,and Departme;

    Biosystems Research Department,Sandia National Laboratories,Livermore,California,Institute of Molecular Biophysics,The National High Magnetic Field Laboratory,Department of Biological Sciences,Florida State University,Tallahassee,Florida,and Departme;

    Biosystems Research Department,Sandia National Laboratories,Livermore,California,Institute of Molecular Biophysics,The National High Magnetic Field Laboratory,Department of Biological Sciences,Florida State University,Tallahassee,Florida,and Departme;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学;
  • 关键词

  • 入库时间 2022-08-18 03:24:03

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