Stereoselective Synthesis of Vinylsilanes by a Gold(I)-Catalyzed Acetylenic Sila-Cope Rearrangement

摘要

Recent advances have dramatically increased the utility of organosilanes and silanolates as reagents for metal-catalyzed cross-coupling reactions.The application of these reactions to stereo-selective olefin synthesis is contingent on efficient and selective methods for the construction of vinylsilanes.Metal-mediated stereoselective addition to alkynes is commonly employed for this purpose.