2-Azaadamantane N-Oxyl(AZADO)and 1-Me-AZADO:Highly Efficient Organocatalysts for Oxidation of Alcohols

摘要

The oxidation of alcohols to their corresponding carbonyl compounds is a pivotal transformation in organic chemistry.The recent global demand for attenuating environmental stress has spurred much effort directed toward the development of green oxidation processes that fulfill the requirements for practical applications.The 2,2,6,6-tetramethyl-l-piperidinyloxy [TEMPO(1),a nitroxyl radical]-catalyzed oxidation method has attracted attention in many areas of synthetic organic chemistry because it enables the use of various safe bulk oxidants,thereby enabling a safe and extremely efficient oxidation of alcohols with considerable operational simplicity.