Magnetic Glyco-nanoparticles: A Unique Tool for Rapid Pathogen Detection, Decontamination, and Strain Differentiation

摘要

The appealing mechanisms by which nanocomposites knit biomolecules not only lend credence in designing novel nanosensors but considerably advance medical applications. Recent headline news about Escherichia coli (E. coli) contamination in produce and Bacillus anthracis attacks pinpoint the urgent need for an effective method for microbial decontamination and rapid detection without time-consuming cell culturing. It is known that many bacteria use mammalian cell surface carbohydrates as anchors for attachments, which subsequently results in infection. The unique combination of magnetic nanocomposites and diverse carbohydrate bioactivities prompts us to embark on a biosensing research program.