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Patterning Nanodomains With Orthogonal Functionalities: Solventless Synthesis Of Self-sorting Surfaces

机译:具有正交功能的纳米域图案化:无溶剂合成的自排序表面

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摘要

Designed bioactive patterned functional surfaces can offer advantageous properties such as controlled adsorption and site-specific affinity. In particular, area-selective functionalization of multiple components onto a predesigned surface is highly desirable. Such a system can be utilized to detect and identify more than one analyte in biosensor applications, which enables fabrication of more effective biodevices. Moreover, the multifunctional surface can be used as a template to monitor the interaction among the adsorbed components from a complex mixture, such as an extracellular environment. To achieve this goal, a highly efficient, orthogonal functionalization scheme with high fidelity is desirable.
机译:设计的生物活性图案功能表面可以提供有利的特性,例如受控的吸附和特定位置的亲和力。特别地,非常需要多个组件在预先设计的表面上的区域选择性功能化。这种系统可用于在生物传感器应用中检测和识别不止一种分析物,从而能够制造更有效的生物设备。而且,多功能表面可以用作模板,以监测来自复杂混合物(例如细胞外环境)的吸附组分之间的相互作用。为了实现该目标,期望具有高保真度的高效正交功能化方案。

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