Ruthenium-catalyzed Enantioselective Carbon-carbon Bond Forming Reaction Via Allenylidene-ene Process: Synthetic Approach To Chiral Heterocycles Such As Chromane, Thiochromane, And 1,2,3,4-tetrahydroquinoline Derivatives

摘要

Heterocycles containing oxygen, sulfur, and nitrogen atoms such as chromane, thiochromane, and 1,2,3,4-tetrahydroquinoline derivatives are widely found in many natural and biologically active compounds. In addition to classical synthetic approaches to these heterocycles, a variety of preparative methods catalyzed by transition metal complexes have been reported including its asymmetric version for the optically active heterocycles.