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Enhancing Cell Recognition by Scrutinizing Cell Surfaces with a Nanoparticle Array

机译:通过用纳米颗粒阵列仔细检查细胞表面来增强细胞识别

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摘要

We report a dual-ligand nanoparticle array approach for discerning cells that have different surface receptor profiles surrounding a common primary receptor expressed at high or low levels. The achieved differentiation provides nanoparticles the ability for potential applications in treatment of patients at a personalized medicine level for drug delivery and radiation therapy with a much better safety profile.
机译:我们报告了一种双配体纳米颗粒阵列方法,用于辨别具有以高或低水平表达的常见主要受体周围不同表面受体概况的细胞。所实现的分化为纳米颗粒提供了在个性化药物水平上治疗患者的潜在应用的能力,从而具有更好的安全性,可用于药物递送和放射治疗。

著录项

  • 来源
    《Journal of the American Chemical Society》 |2011年第4期|p.680-682|共3页
  • 作者单位

    Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States;

    Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States,School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China;

    Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States;

    Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States;

    Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States,School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
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  • 入库时间 2022-08-18 03:14:06

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