Rhodium-Catalyzed Ring Opening of Benzocyclobutenols with Site- Selectivity Complementary to Thermal Ring Opening

摘要

A rhodium catalyst induced ring opening of benzocyclobutenols with selective cleavage of the C(sp~2)-C(sp~3) bond adjacent to the hydroxyl group. The site-selectivity markedly contrasted with that of their thermal ring-opening reaction. The rhodium-catalyzed ring opening led to the development of a new alkyne insertion reaction constructing a dihydronaphthalene framework.