Palladium(Ⅲ)-Catalyzed Fluorination of Arylboronic Acid Derivatives

摘要

A practical, palladium-catalyzed synthesis of aryl fluorides from arylboronic acid derivatives is presented. The reaction is operationally simple and amenable to multigram-scale synthesis. Evaluation of the reaction mechanism suggests a single-electron-transfer pathway, involving a Pd(Ⅲ) intermediate that has been isolated and characterized.