Ligand-Controlled Asymmetric Arylation of Aliphatic α-Amino Anion Equivalents

摘要

A palladium-catalyzed asymmetric arylation of 9-aminofluorene-derived imines using a chiral dialkyl-biaryl phosphine as the supporting ligand has been developed. This transformation allows for enantioselective access to a diverse range of α-branched benzylamines.