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Controlled Formation and Binding Selectivity of Discrete Oligo(methyl methacrylate) Stereocomplexes

机译:离散低聚(甲基丙烯酸甲酯)立体配合物的形成和结合选择性

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摘要

The triple-helix stereocomplex of poly(methyl methacrylate) (PMMA) is a unique example of a multistranded synthetic helix that has significant utility and promise in materials science and nanotechnology. To gain a fundamental understanding of the underlying assembly process, discrete stereoregular oligomer libraries were prepared by combining stereospecific polymerization techniques with automated flash chromatography purification. Stereocomplex assembly of these discrete building blocks enabled the identification of (1) the minimum degree of polymerization required for the stereocomplex formation and (2) the dependence of the helix crystallization mode on the length of assembling precursors. More significantly, our experiments resolved binding selectivity between helical strands with similar molecular weights. This presents new opportunities for the development of next-generation polymeric materials based on a triple-helix motif.
机译:聚(甲基丙烯酸甲酯)(PMMA)的三螺旋立体复合物是多链合成螺旋的独特实例,在材料科学和纳米技术中具有重要的用途和前景。为了对基础的组装过程有一个基本的了解,通过将立体有规聚合技术与自动快速色谱纯化相结合来制备离散的立体有规低聚物库。这些离散结构单元的立体复合物组装使得能够鉴定(1)立体复合物形成所需的最小聚合度,和(2)螺旋结晶模式对组装前体长度的依赖性。更重要的是,我们的实验解决了分子量相似的螺旋链之间的结合选择性。这为开发基于三螺旋基序的下一代聚合物材料提供了新的机遇。

著录项

  • 来源
    《Journal of the American Chemical Society》 |2018年第5期|1945-1951|共7页
  • 作者单位

    Materials Research Laboratory, Department of Materials, and Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California 93106, United States,Department of Chemical Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia;

    Materials Research Laboratory, Department of Materials, and Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California 93106, United States;

    Materials Research Laboratory, Department of Materials, and Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California 93106, United States;

    Materials Research Laboratory, Department of Materials, and Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California 93106, United States;

    Materials Research Laboratory, Department of Materials, and Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California 93106, United States;

    Materials Research Laboratory, Department of Materials, and Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California 93106, United States;

    Materials Research Laboratory, Department of Materials, and Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California 93106, United States;

    Materials Research Laboratory, Department of Materials, and Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California 93106, United States;

    Materials Research Laboratory, Department of Materials, and Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California 93106, United States;

    Materials Research Laboratory, Department of Materials, and Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California 93106, United States;

    Materials Research Laboratory, Department of Materials, and Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California 93106, United States;

    Materials Research Laboratory, Department of Materials, and Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California 93106, United States;

    Department of Chemical Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia;

    Materials Research Laboratory, Department of Materials, and Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, California 93106, United States;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
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  • 入库时间 2022-08-18 03:07:18

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