Effects of methylene blue on the blood pressure and cgmp of endotoxic shock rabbits

摘要

Objective To investigate the effect of methylene blue (MB) on the blood pressure and cGMP of endotoxic shock. Methods An experiment was performed on 16 New Zealand rabbits suffering from endotoxic shock, in which 8 were distributed to the trial group (MB infusion) and another 8 to the control group (normal saline). The mean arterial pressure (MAP), plasma cyclic monophosphate guanylate (cGMP), and arterial natriuretic factor (ANF) in the two groups were observed.