Synthesis of a Series of Focally-Substituted Organothiol Dendrons

摘要

The synthesis of new organothiol-functionalized dendrons of generation 1—4 is described. Several modifications to the original method for preparation of dendrons are detailed that were found to improve the yield and aid in scale-up. A particularly advantageous method for preparation of an aromatic thiol is reported and is employed in this reaction sequence. Several uses of these dendrons are anticipated and briefly described.