Compared reactivity of heterocyclic enaminons: photochemical and palladiu catalyzed synthesis of 6,7,8,9-tetrahydro-5H-pyrido[3,2-b]indol-9-ones

摘要

Interest in the chemistry of tetreahydrocarbazolone derivatives has increased since these structures have been found to represent an interesting class of bioactive heterocyclic compounds and are implicated in the elabo- ration of natural compounds related to several classes of indole alkaloids. For example, the synthetic drug ondansetron, a 3-substituted 1,2,3,4-tetrahydro-1H-car- bazol-4-one, is a potent antagonist of 5HT_3 receptor.