Tandem aldol-tishchenko reactions of lithium enolates: highly stereoselective method for diol and triol synthesis

摘要

The reactions of metal enolates constitute important methods for the construction of carbon-carbon bonds. Early investigations of aldol reactions employing lithium Ketone enolates provided significant mechanistic infor- Mation, although these reactions are not generally as Stereoselective as those of other enolates.