Studies to ward lipid A: synthesis of differentially protected disaccharide fragments

摘要

Disaccharides containing two glucosamine units are readily synthesized where the two amine functionalities are orthogonally protected as the tetrachlorophthaloyl and pent-4-enoyl moieties. The 1-6 linked disaccharide has the potential to be developed toward a series of biologically Interesting lipid a analogs.