Regio- and Stereoselective Deuteration of Allylic Chlorides Controlled by Neighboring Alcohol or Ether Groups

摘要

We have shown that regio- and stereo-control can be achieved by use of an adjacent alcohol or the corresponding silyl ether in the reduction of allylic chlorides. This methodology should prove to be of importance for the regio- and stereoselective. synthesis of deuterated compounds.