A High-Yield,One-Step Synthesis of o-Phenylene Ethynylene Cyclic Trimer via Precipitation-Driven Alkyne Metathesis

摘要

A shape-persistent,conjugated o-phenylene ethynylene cyclic trimer was prepared in one step from tetrasubstituted benzene monomer 4 in 86% isolated yield through precipitation-driven alkyne metathesis.The template-free,selective generation of the molecular triangle 5 is a thermodynami-cally favored process and under equilibrium control.A novel tetrameric macrocycle 7 was generated via scrambling metathesis between tricycle 5 and hexacycle 6 using this dynamic covalent chemistry.