Palladium-Catalyzed Selective 2,3-Diarylation of alpha,alpha-Disubstituted 3-Thiophenemethanols via Cleavage of C-H and C-C Bonds

摘要

alpha,alpha-Disubstituted 3-thiophenemethanols undergo selective diarylation accompanied by cleavage of the C-H and C-C bonds of the 2- and 3-positions,respectively,upon treatment with aryl bromides in the presence of a palladium catalyst to give the corresponding 2,3-diarylthiophenes in good yields.