N,N-Bond-Forming Heterocyclization: Synthesis of 3-Alkoxy-2H-indazoles

摘要

A one-step heterocyclization of o-nitrobenzylamines to 3-alkoxy-2H-indazoles is reported.The electronic nature of the nitrophenyl group,the steric and electronic nature of the R~1-functionalized benzylic amine,and the nature of the alcoholic solvent affect the efficiency of this heterocyclization reaction (approx 40- 90%).